Monther Hassan, 28, from the West Bank city of Hebron and Sobhi Zma'ra, 16, from the nearby Halhoul village were taken prisoners by the Israeli army on Tuesday morning.
Troops stormed, searched and ransacked residents' houses in Hebron city and Halhou, before taking the two to unknown locations, their families reported.
The sister of Zma'ra said that troops stormed their house in Halhoul 50 days ago and abducted her19-year old brother who remained in detention until now without charges or trial.